As a background I have been searching for the perfect bike for that last 4 years. The search started in 2013 when I was looking for a sport bike that I could do some serious miles on. I was naturally drawn to the K1300S but when I tried it but it was cumbersome, slow to turn and only felt good going 90-120mph down the interstate - Boy, but what a motor. When I returned the bike the dealer suggested I try a Ducati Multistrada ... unfortunately I am inseam challenged (29") and could barely get my tippy toes on the ground. Then he suggested I try a Diavel. "What's a Diavel?", I asked. He showed me and I said, "That's the ugliest bike I have ever seen." "I know, he replied but they grow on you." I tried it and was smitten, same amazing power of the K1300S but so much lighter and SO MUCH more maneuverable. Since the Diavel purchase I have tried and S1000rr (license/life taker), S1000r (Great fun but, not as much as the Ducati - too clinical/sterile), Ducati Panagale 959 (i found its ridiculous trying to ride that on the road in any kind of traffic ... you could tour on it if you could your average speed up around 100 mph, otherwise its too painful). Fast forward to today after 12,000 miles on the Diavel. I have been considering the R1200RS and the the amazing folks at Erico Motorsports in Denver suggested I try out a Ducati SuperSport S for the weekend! I was able to do a 300+ mile test ride. I road it up in the mountains up to the top of Mt Evans (14,200 ft). I road it about 150 miles on the interstate (I-70 and I-25) and I road it a good 160 miles in the "twisties" of the Colorado mountains. then for fun and comparison I did a quick (15 mile test ride on an R1200RS...I could only get it for 15 miles ... Dang.) So is my take on the two bikes and how they fit with the rest of the world: The SuperSport is the best handling bike for the road (roads not track) period. It is the most confidence inspiring bike I have ever ridden. It is a sport bike that you can sort-of comfortably tour on. Engine: Ducati engines are hard to beat for the thrill and the passion they convey the acceleration of the two bikes was about the same with a slight edge to the Ducati. Transmission: No contest here the RS kills it. Super smooth. Ducati transmission are brutish in comparison. Suspension: The Supersport keeps you inexorably connected to the road in a way that is hard to convey in words. I has to be experienced. There are no surprises, think turn and your are turning, no skips, surprises it makes you feel like Valentio Rossi. You know exactly what is going on beneath your tires down to each pebble underneath them. The RS was very well planted and seemed firm but it did not feel as well connected ... I guess you have to trust the ESA ... Wind: the RS had more buffeting around the helmet at 70-85 mph. I was surprised by this. The Ducati air was clean and the windscreen did a good job of keeping the wind off your chest. At Speed: The RS is more comfortable above 80 mph. The connectedness of the Ducati would get old after a couple of hours and the vibrations increase above 90 ... fast interstate travel - handsdown the RS. In the turns: Hands down the Ducati, but the RS was not far behind and that is saying something. The Ducati is lighter/thinner and is more nimble. Ridding Position: Ducati is slightly more aggressive but not much I am 5'8". Seats: Ducati not bad the RS better more plush but I only spent 15 miles in it. Fun Factor: The Ducati was more fun but that fun and connection with the road comes at a price. I admit I smiled big when I got on the RS and whooshed down the highway at 90 mph. It all boils down to your mission statement: Going to carry a pillion?: Go RS Going to do longer trips (say more than 3-400 miles/day)?: Go RS Have to ride hundred of miles on the interstate: Go RS Don't want to mess with a chain: Go RS Need heated grips: Go RS But if you have some amazing mountain roads like I do with in a half hour and you do mostly weekend trips (300 mile/day or less) buy the Ducati. Both will make you smile. The Ducati will Make you smile more until you hit about 300 miles then the RS will make you smile.